USE OF CARNOSINE IN THE PREVENTION OF CARDIOMETABOLIC RISK FACTORS IN OVERWEIGHT AND OBESE INDIVIDUALS: STUDY PROTOCOL FOR A RANDOMISED, DOUBLE-BLIND PLACEBO-CONTROLLED TRIAL

Use of carnosine in the prevention of cardiometabolic risk factors in overweight and obese individuals: study protocol for a randomised, double-blind placebo-controlled trial

Introduction Carnosine, an over the counter food supplement, has been shown to improve glucose metabolism as well as cardiovascular risk factors in animal and human studies through its anti-inflammatory, antioxidative, airbrush graphic tee antiglycating and chelating properties.The aim of this study is to establish if carnosine supplementation impr

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One-pot three-component tandem annulation of 4-hydroxycoumarine with aldehyde and aromatic amines using graphene oxide as an efficient catalyst

Abstract A convenient and efficient solvent-free, facile, one-pot three-component graphene oxide catalysed approach has been described for the synthesis of chromeno-[4,3-b]quinolin-6-one derivatives from 4-hydroxycoumarin with aldehydes and aromatic amines.Graphene oxide (GO) has proved to be peperomia double duty a new class of heterogeneous carbo

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Role of the Combination of Cyclin-Dependent Kinase Inhibitors (CDKI) and Radiotherapy (RT) in the Treatment of Metastatic Breast Cancer (MBC): Advantages and Risks in Clinical Practice

Targeting cell cycle has become the gold standard for metastatic breast cancer (MBC), being cyclin-dependent kinase inhibitors (CDKIs) cornerstones of its treatment, alongside radiotherapy (RT).To date, no definite evidence regarding safety and efficacy of the combination of CDKIs plus radiotherapy (RT) is currently available.Purpose of this review

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A Comparison Study of Explicit and Implicit 3-D Transient Electromagnetic Forward Modeling Schemes on Multi-Resolution Grid

This study compares the efficiency of 3-D transient electromagnetic forward modeling schemes on the multi-resolution grid for various modeling scenarios.We developed time-domain finite-difference modeling based on the explicit scheme earlier.In this work, we additionally implement 3-D transient electromagnetic forward modeling using the backward Eu

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